CasImg
醋酸去氢表雄酮
产品纠错
CAS号:853-23-6 | 英文名称:Dehydroepiandrosterone acetate
分子式
分子量
EINECS号
MDL
Smiles
InChIKey
乙二醇化学百科
基本信息
中文名称 醋酸去氢表雄酮
英文名称 Dehydroepiandrosterone acetate
CAS号 853-23-6
分子式 C21H30O3
分子量 330.47
EINECS号 212-714-1
InChI InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3
SMILES C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r|
物化性质
熔点 168-170 °C(lit.)
沸点 407.89°C (rough estimate)
密度 1.0998 (rough estimate)
蒸气压 0Pa at 20℃
折射率 1.5192 (estimate)
LogP 5.1 at 20℃
溶解度 可溶于氯仿、DMSO(微溶)、甲醇(微溶)
形态 固体
颜色 白色至类白色
旋光性 (optical activity) [α]20/D +2.4°, c = 2 in ethanol
水溶解性 11.5mg/L(temperature not stated)
安全信息
安全说明 22-24/25
WGK Germany 3
RTECS号 BV8396810
生产及用途
Dehydroepiandrosterone 3-acetate 是雄性激素/雌性激素的前体物质,能够调节脊椎动物的攻击性行为。

Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.

用途 
用于合成甾体激素药物
用途 
醋酸去氢表雄酮是合成各种激素、计划生育用品等甾体激素类药物的重要中间体,由它可合成睾丸素、甲基睾丸素、雌二醇、雌三醇
产品供应商
853-23-6
上海阿拉丁生化科技股份有限公司
2023-10-02

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