| ||||||||||||||||||||||||||||||||||||||||||||||
![]()
CAS号:526-31-8
|
英文名称:L-ABRINE
分子式
C12H14N2O2
分子量
218
EINECS号
208-388-5
MDL
MFCD00005645
Smiles
C(O)(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC
InChIKey
CZCIKBSVHDNIDH-NSHDSACASA-N
乙二醇化学百科
基本信息
物化性质
安全信息
生产及用途
L-Abrine (N-Methyl-L-tryptophan)是相思子根部的毒性清蛋白,可抑制核糖体。 L-(+)-Abrine is a marker for abrin poisoning. A strong indication for abrin poisoning is the presence of the chemical maker L-(+)-Abrine, which can survive metabolism in significant amounts making it detectable in human urine.
Abrin is a toxic protein found in the jequirity seed. L-(+)-Abrine (L-Abrine) is also found in the jequirity seed and can be used as a biomarker for abrin exposure. An animal study is designed to monitor the excretion and recovery of L-(+)-Abrine in 20 rats. The animals are exposed to one of three concentrations of L-(+)-Abrine, a single high concentration of L-tryptophan, or no agent (control). The low L-(+)-Abrine dose corresponds to 0.63 LD 50 i.p. abrin in mice, assuming a concentration ratio of 1:4 of abrin to L-(+)-Abrine and an LD 50 for abrin of 20 μg/kg. The mid and high L-(+)-Abrine (250 and 400 μg/kg) doses are included to ensure that the target analyte can be detected and tracked over the course of the experiment.
用途 一种在体外表现出自由基清除和抗氧化剂特性的吲哚氨基酸。
上下游产品
上游产品共计:0个
下游产品共计:0个
相关产品
|
||||||||||||||||||||||||||||||||||||||||||||||
本网站展示的所有产品仅用于工业制造、技术研发、科学研究,所有产品非药品不可食用,依据国家相关法规及平台管理要求,购买相关危险物品应取得有效的资质、资格条件。 参考《应急管理部等多部门关于加强互联网销售危险化学品安全管理的通知 (应急〔2022〕119号)》 和《互联网危险物品信息发布管理规定》 Copyright © 2021-2025 chemhome123版权所有 |冀ICP备2024096099号- 1|冀公安备13042302000143号|互联网增值电信业务经营许可证:冀B2-20250121 |药品、 医疗器械互联网信息服务备案凭证备案号:(冀)-非经营性-2025-0099 |