Biperiden(KL 373)有抗帕金森症活性，是中枢M1胆碱受体阻断剂。结晶体。熔点112-116℃（101℃）。不易溶于水，微溶于乙醇，易溶于甲醇。该品的盐酸盐（C21H29NO·HCI）又称安克痉（Akineton，Akinophyl)，为白色结晶。约275℃分解，也有报道其熔点为238℃。该品为抗震颤麻痹药、解痉药。小鼠口服LD50为545mg/kg，静脉注射为56mg/kg。Biperiden is antiparkinsonian; non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkinson鈥瞫 Disease (postencephalitic, idiopathic, and arter iosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy.以环戊二烯为原料，先与氯乙烯合成氯代双环庚烯，再与镁和乙醚反应，得双环庚烯镁化氯，最后与β-哌啶苯丙酮缩合制得比哌立登。β-哌啶苯丙酮的制备：以苯乙酮为原料与哌啶盐酸盐、甲醛、二甲胺经曼氏反应得到。有毒物品中毒口服-大鼠 LD50: 750 毫克/公斤; 口服-小鼠 LD50: 530 毫克/公斤可燃; 燃烧产生有毒氮氧化物烟雾通风低温干燥干粉,泡沫,沙土,二氧化碳, 雾状水