1-羟基蒽醌 1-Hydroxy anthraquinone CAS#:129-43-1

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首页化工产品目录有机原料醌类化合物 1-羟基蒽醌

1-羟基蒽醌

产品纠错

CAS号：129-43-1 | 英文名称：1-Hydroxy anthraquinone

分子式 C₁₄H₈O₃

分子量 224

EINECS号 204-946-7

MDL MFCD00058946

Smiles C1(O)=C2C(C(=O)C3=C(C2=O)C=CC=C3)=CC=C1

InChIKey BTLXPCBPYBNQNR-UHFFFAOYSA-N

乙二醇化学百科

基本信息

物化性质

安全信息

生产及用途

1-Hydroxyanthraquinone 是具有口服活性的天然产物，可来源于一些植物如 Tabebuia avellanedae，具有致癌作用。

1-Hydroxyanthraquinone (HA) generates strong DNA repair response and is carcinogenic in rats.

Animal Model:	Thirty rats.
Dosage:	1% HA in diet.
Administration:	Diet.
Result:	Associated with decreased weight gain which was particularly marked towards the termination of experiment. One of the 30 rats in group 1 (experimental group) died of pneumonia 243 days after the start of experiment. A second rat died in an unnourished state at day 280, demonstrating a large tumor in the colon. Seven animals of the group died spontaneously or were sacrificed upon becoming moribund between 335 and 462 days. A total of 21 rats of group 1 survived until the end of experiment (mean value of total intake of HA/rat was 76.8 g).