CAS号：2746-81-8
|
英文名称：fluphenazine O-enantate
分子式
C29H38F3N3O2S
分子量
550
EINECS号
2203850
MDL
MFCD00866641
Smiles
InChIKey
fluphenazine O-enantate化学百科
基本信息
| 中文名称 | fluphenazine O-enantate |
| 英文名称 | fluphenazine O-enantate |
| CAS号 | 2746-81-8 |
| 分子式 | C29H38F3N3O2S |
| 分子量 | 549.698 |
| EINECS号 | 2203850 |
物化性质
| 熔点 | 184.5°C |
| 沸点 | 629.4±55.0 °C(Predicted) |
| 密度 | 1.1661 (estimate) |
| 溶解度 | 几乎不溶于水，极易溶于乙醇和二氯甲烷，易溶于甲醇。 |
| 酸度系数(pKa) | 7.32±0.10(Predicted) |
安全信息
| 危险品运输编号 | 3249 |
| 危险等级 | 6.1(b) |
| 包装类别 | III |
生产及用途
Fluphenazine enanthate 是第一种长效抗精神病药物，用于研究精神分裂症。
Fluphenazine enanthate (2,4, 8 mg/kg; IM) significant inhibition of the avoidance performance is observed as long as 16, 23, and 28 days, respectively.
Fluphenazine enanthate (8 mg/kg) drinking behavior is almost completely suppressed for 24 hours immediately following the administration.
Fluphenazine enanthate (8 mg/kg) produces transient body weight Iosses in the rats.
| Animal Model: | Fifty-four male adult rats of Wistar strain |
| Dosage: | 2, 4, and 8 mg/kg |
| Administration: | Index medicus (IM ) |
| Result: | Three doses of Fluphenazine enanthate significant inhibition of the avoidance performance was observed as long as 16, 23, and 28 days, respectively. |
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