| 中文名称 | L-半胱亚磺酸 |
| 英文名称 | L-CYSTEINESULFINIC ACID MONOHYDRATE |
| CAS号 | 207121-48-0 |
| 分子式 | HO2SCH2CH(NH2)CO2HH2O |
| 分子量 | 171.17 |
| EINECS号 | 623-116-9 |
| 熔点 | 163 °C (dec.)(lit.) |
| 溶解度 | 可溶于酸性水溶液（轻微）、甲醇（轻微）、水（轻微） |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
| 旋光性 (optical activity) | [α]25/D +24°, c = 1 in 1 M HCl |
| 稳定性 | 对温度敏感 |
| 危险品标志 | Xi |
| 危险类别码 | 36/37/38 |
| 安全说明 | 26-36 |
| WGK Germany | 3 |
| 海关编码 | 2930901300 |
|
mGluR1 3.92 (pEC 50 ) |
mGluR2 3.9 (pEC 50 ) |
mGluR4 2.7 (pEC 50 ) |
mGluR5 4.6 (pEC 50 ) |
mGluR6 4.0 (pEC 50 ) |
mGluR8 3.94 (pEC 50 ) |
L-Cysteinesulfinic acid is an endogenous agonist of a metabotropic receptor coupled to stimulation of phospholipase D (PLD) activity. L-CSA is an endogenous agonist of the PLD-coupled metabotropic excitatory amino acids (EAA) receptor. L-CSA selectively activates the PLD-coupled receptor. 1 mM L-CSA induces a significant increase in PLD activity in hippocampal slices, whereas 1 mM concentrations of L-glutamate, L-aspartate, and L-HCA are without effect. L-CSA elicits a dose-dependent increase in PLD activity in rat hippocampal slices in the presence of iGluR antagonists, with an approximate EC 50 of 500 uM. The PLD response induced by 1 mM L-CSA is not significantly decreased in the presence of 1 uM tetrodotoxin, suggesting that this response is not dependent upon L-CSA-induced increases in cell firing.